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NICOTINE
Descriptors Found:
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DeCS
Descriptor
English
:
Nicotine
Descriptor
Spanish
:
Nicotina
Descriptor
Portuguese
:
Nicotina
Tree Number:
D03.132.760.570
D03.383.725.518
SP4.011.092.763
SP4.041.432.563
Definition
English
:
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates
neurons
and ultimately blocks
synaptic transmission
.
Nicotine
is also important medically because of its presence in
tobacco
smoke.
Indexing Annotation
English
:
/biosyn permitted if by plant
Pharmacological Action:
Ganglionic Stimulants
Nicotinic Agonists
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
urine
Record Number:
9723
Unique Identifier:
D009538
Occurrence in VHL
:
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