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PROGLUCAGON
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DeCS
Descriptor
English
:
Proglucagon
Descriptor
Spanish
:
Proglucagón
Descriptor
Portuguese
:
Proglucagon
Tree Number:
D06.472.317.469
D06.472.699.587.469
D12.644.548.586.469
D12.776.811.700
Definition
English
:
The common precursor polypeptide of pancreatic
GLUCAGON
and intestinal
GLUCAGON-LIKE PEPTIDES
.
Proglucagon
is the 158-amino acid segment of preproglucagon without the N-terminal signal sequence.
Proglucagon
is expressed in the
PANCREAS
;
INTESTINES
; and the
CENTRAL NERVOUS SYSTEM
. Posttranslational processing of
proglucagon
is tissue-specific yielding numerous bioactive
peptides.
History Note
English
:
2007 (2006); for GLUCAGON PRECURSOR use GLUCAGON PRECURSOR (NM) 1977-2007
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
50566
Unique Identifier:
D052336
Occurrence in VHL
:
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