Search on:
ANGIOPOIETIN-2
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Angiopoietin-2
Descriptor
Spanish
:
Angiopoyetina 2
Descriptor
Portuguese
:
Angiopoietina-2
Tree Number:
D12.644.276.100.100.200
D12.776.467.100.100.200
D23.529.100.100.200
Definition
English
:
An angiopoietin that is closely related to
ANGIOPOIETIN-1
. It binds to the TIE-2 RECEPTOR without receptor stimulation and antagonizes the effect of
ANGIOPOIETIN-1
. However its antagonistic effect may be limited to cell receptors that occur within the vasculature.
Angiopoietin-2
may therefore play a
role
in
down-regulation
of
BLOOD
VESSEL branching and sprouting.
History Note
English
:
2004; use ANGIOPOIETIN-2 (NM) 1997-2003
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
urine
Record Number:
38239
Unique Identifier:
D042702
Occurrence in VHL
:
Similar:
DeCS
SciELO
LILACS
LIS