Search on: ANGIOSTATINS 
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Descriptor English:   Angiostatins 
Descriptor Spanish:   Angiostatinas 
Descriptor Portuguese:   Angiostatinas 
Tree Number:   D08.622.610.500
D12.644.276.100.450.500
D12.776.124.790.223.580.500
D12.776.377.715.182.580.500
D12.776.467.100.450.500
D23.529.100.450.500
Definition English:   Circulating 38-kDa proteins that are internal peptide fragments of PLASMINOGEN. The name derives from the fact that they are potent ANGIOGENESIS INHIBITORS. Angiostatins contain four KRINGLE DOMAINS which are associated with their potent angiostatic activity. 
Pharmacological Action:   Angiogenesis Inhibitors
Antineoplastic Agents
 
History Note English:   2004; use ANGIOSTATINS (NM) 1994-2003 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
urine  
Record Number:   38124 
Unique Identifier:   D043168 

Occurrence in VHL: 		 

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