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O-ACETYL-ADP-RIBOSE
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DeCS
Descriptor
English
:
O-Acetyl-ADP-Ribose
Descriptor
Spanish
:
O-Acetil-ADP-Ribosa
Descriptor
Portuguese
:
O-Acetil-ADP-Ribose
Synonyms
English
:
Adenosine-Diphosphate-Ribose, O-Acetyl-
Tree Number:
D03.438.759.646.138.124.070.125.040
D09.408.620.569.070.125.040
D13.695.667.138.124.070.125.040
D13.695.827.068.124.070.125.040
D13.695.827.708.070.125.040
Definition
English
:
An acetyl ester of
ADENOSINE DIPHOSPHATE RIBOSE
formed during NAD-dependent deacetylation of
proteins
by
SIRTUINS
. The acetate group resides on the
ribose
ring where nicotinamide was cleaved from
NAD
during the reaction. Several isomers of
O-acetyl-ADP-ribose
have been isolated from the reaction.
History Note
English
:
2003; use O-ACETYL-ADP-RIBOSE (NM) 2001-2002
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
urine
Record Number:
37362
Unique Identifier:
D038961
Occurrence in VHL
:
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